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1

In vivo MRI visualization of release from liposomes triggered by local application of pulsed low-intensity non-focused ultrasound

Rizzitelli, Silvia, Giustetto, Pierangela, Boffa, Cinzia, Delli Castelli, Daniela, Cutrin, Juan Carlos, Aime, Silvio, Terreno, Enzo

Journal:

Nanomedicine: Nanotechnology, Biology and Medicine

Year:

2014

Language:

english

File:

PDF, 587 KB

english, 2014

2

Studies to enhance the hyperpolarization level in PHIP-SAH-produced C13-pyruvate

Cavallari, Eleonora, Carrera, Carla, Aime, Silvio, Reineri, Francesca

Journal:

Journal of Magnetic Resonance

Year:

2018

Language:

english

File:

PDF, 884 KB

english, 2018

3

Direct NMR Spectroscopic Observation of a Lanthanide-Coordinated Water Molecule whose Exchange Rate Is Dependent on the Conformation of the Complexes

Silvio Aime, Alessandro Barge, Mauro Botta, Alvaro S. De Sousa, David Parker

Journal:

Angewandte Chemie International Edition

Year:

1998

Language:

english

File:

PDF, 83 KB

english, 1998

4

ChemInform Abstract: Pushing the Sensitivity Envelope of Lanthanide-Based Magnetic Resonance Imaging (MRI) Contrast Agents for Molecular Imaging Applications

Silvio Aime, Daniela Delli Castelli, Simonetta Geninatti Crich, Eliana Gianolio, Enzo Terreno

Journal:

Year:

2009

File:

PDF, 15 KB

2009

5

The «How to…»: a new type of paper!

Proffessor Silvio Aime, Proffessor Robert N. Muller

Journal:

Contrast Media & Molecular Imaging

Year:

2006

Language:

english

File:

PDF, 44 KB

english, 2006

6

Encoding the frequency dependence in MRI contrast media: the emerging class of CEST agents

Enzo Terreno, Daniela Delli Castelli, Silvio Aime

Journal:

Contrast Media & Molecular Imaging

Year:

2010

Language:

english

File:

PDF, 1019 KB

english, 2010

7

MRI of cells and mice at 1 and 7 Tesla with Gd-targeting agents: when the low field is better!

Simonetta Geninatti-Crich, Ibolya Szabo, Diego Alberti, Dario Longo, Silvio Aime

Journal:

Contrast Media & Molecular Imaging

Year:

2011

Language:

english

File:

PDF, 191 KB

english, 2011

8

Biodistribution of gadolinium-based contrast agents, including gadolinium deposition

Silvio Aime, Peter Caravan

Journal:

Journal of Magnetic Resonance Imaging

Year:

2009

Language:

english

File:

PDF, 270 KB

english, 2009

9

Paramagnetic water proton relaxation enhancement: From contrast agents in MRI to reagents for quantitative “in vitro” assays

Silvio Aime, Mauro Botta, Giuseppe Ermondi, Mauro Fasano, Enzo Terreno

Journal:

Magnetic Resonance Imaging

Year:

1992

Language:

english

File:

PDF, 475 KB

english, 1992

10

Current concepts on hyperpolarized molecules in MRI

Alessandra Viale, Silvio Aime

Journal:

Current Opinion in Chemical Biology

Year:

2010

Language:

english

File:

PDF, 411 KB

english, 2010

11

High Relaxivity Gadolinium Hydroxypyridonate−Viral Capsid Conjugates: Nanosized MRI Contrast Agents 1

Datta, Ankona, Hooker, Jacob M., Botta, Mauro, Francis, Matthew B., Aime, Silvio, Raymond, Kenneth N.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 1.42 MB

english, 2008

12

PAMAM Dendrimeric Conjugates with a Gd−DOTA Phosphinate Derivative and Their Adducts with Polyaminoacids: The Interplay of Global Motion, Internal Rotation, and Fast Water Exchange

Rudovský, Jakub, Botta, Mauro, Hermann, Petr, Hardcastle, Kenneth I., Lukeš, Ivan, Aime, Silvio

Journal:

Bioconjugate Chemistry

Year:

2006

Language:

english

File:

PDF, 309 KB

english, 2006

13

First 17 O NMR Observation of Coordinated Water on Both Isomers of [Eu(DOTAM)(H 2 O)] 3+ : A Direct Access to Water Exchange and its Role in the Isomerization 1

Dunand, Frank A., Aime, Silvio, Merbach, André E.

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 117 KB

english, 2000

14

Notes. Carbon-13 and oxygen-17 nuclear magnetic resonance relaxation studies of [M3(CO)12] derivatives (M = Fe, Ru, or Os)

Aime, Silvio, Botta, Mauro, Gobetto, Roberto, Osella, Domenico

Journal:

Journal of the Chemical Society Dalton Transactions

Year:

1988

Language:

english

File:

PDF, 230 KB

english, 1988

15

NMR, Relaxometric, and Structural Studies of the Hydration and Exchange Dynamics of Cationic Lanthanide Complexes of Macrocyclic Tetraamide Ligands

Aime, Silvio, Barge, Alessandro, Bruce, James I., Botta, Mauro, Howard, Judith A. K., Moloney, Janet M., Parker, David, de Sousa, Alvaro S., Woods, Mark

Journal:

Journal of the American Chemical Society

Year:

1999

Language:

english

File:

PDF, 183 KB

english, 1999

16

A New Class of Contrast Agents for Magnetic Resonance Imaging Based on Selective Reduction of Water-T2 by Chemical Exchange

AIME, SILVIO, NANO, RITA, GRANDI, MAURIZIO

Journal:

Investigative Radiology

Year:

1988

File:

PDF, 2.07 MB

1988

17

Large photoacoustic effect enhancement for ICG confined inside MCM-41 mesoporous silica nanoparticles

Ferrauto, Giuseppe, Carniato, Fabio, Di Gregorio, Enza, Tei, Lorenzo, Botta, Mauro, Aime, Silvio

Journal:

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

18

A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol

Wu, Yin, Zhou, Iris Y., Igarashi, Takahiro, Longo, Dario L., Aime, Silvio, Sun, Phillip Zhe

Journal:

Magnetic Resonance in Medicine

Year:

2017

Language:

english

File:

PDF, 419 KB

english, 2017

19

Inner-sphere water and hydrogen bonds in lanthanide DOTAM complexes. A neutron diffraction study

Bombieri, Gabriella, Artali, Roberto, Mason, Sax A., McIntyre, Garry J., Mortillaro, Armando, Aime, Silvio

Journal:

Inorganica Chimica Acta

Year:

2017

Language:

english

File:

PDF, 926 KB

english, 2017

20

1H-NMR and MALDI-TOF MS as metabolomic quality control tests to classify platelet derived medium additives for GMP compliant cell expansion procedures

Agostini, Francesco, Ruzza, Marta, Corpillo, Davide, Biondi, Luca, Acquadro, Elena, Canepa, Barbara, Viale, Alessandra, Battiston, Monica, Serra, Fabrizio, Aime, Silvio, Mazzucato, Mario, Hagemeyer, C

Journal:

Year:

2018

Language:

english

File:

PDF, 4.24 MB

english, 2018

21

Manganese-enhanced MRI (MEMRI) in breast and prostate cancers: Preliminary results exploring the potential role of calcium receptors

Baio, Gabriella, Fabbi, Marina, Cilli, Michele, Rosa, Francesca, Boccardo, Simona, Valdora, Francesca, Salvi, Sandra, Basso, Luca, Emionite, Laura, Gianolio, Eliana, Aime, Silvio, Neumaier, Carlo Eman

Journal:

Year:

2020

File:

PDF, 3.41 MB

2020

22

Supramolecular adducts between macrocyclic Gd (III) complexes and polyaromatic systems: a route to enhance the relaxivity through the formation of hydrophobic interactions.

Di Gregorio, Enza, Lattuada, Luciano, Maiocchi, Alessandro, Aime, Silvio, Ferrauto, Giuseppe, Gianolio, Eliana

Journal:

Chemical Science

Year:

2021

File:

PDF, 1.87 MB

2021

23

NMR relaxometric studies of Gd(III) complexes with heptadentate macrocyclic ligands

Silvio Aime, Mauro Botta, Simonetta Geninatti Crich, Giovanni Giovenzana, Roberto Pagliarin, Massimo Sisti, Enzo Terreno

Journal:

Magnetic Resonance in Chemistry

Year:

1998

Language:

english

File:

PDF, 275 KB

english, 1998

24

Determination of the Prototropic Exchange Rate at the Water Molecule Coordinated to an Anionic Paramagnetic GdIII Chelate

Silvio Aime, Simonetta Geninatti Crich, Eliana Gianolio, Enzo Terreno, Andrea Beltrami, Fulvio Uggeri

Journal:

European Journal of Inorganic Chemistry

Year:

1998

Language:

english

File:

PDF, 519 KB

english, 1998

25

Direkter NMR-spektroskopischer Nachweis eines Lanthanoid-koordinierten Wassermoleküls, dessen Austauschgeschwindigkeit von der Konfiguration des Komplexes abhängt

Silvio Aime, Alessandro Barge, Mauro Botta, Alvaro S. De Sousa, David Parker

Journal:

Angewandte Chemie

Year:

1998

Language:

german

File:

PDF, 72 KB

german, 1998

26

A p(O2)-Responsive MRI Contrast Agent Based on the Redox Switch of Manganese(II / III) – Porphyrin Complexes

Silvio Aime, Mauro Botta, Eliana Gianolio, Enzo Terreno

Journal:

Angewandte Chemie

Year:

2000

Language:

english

File:

PDF, 109 KB

english, 2000

27

Spectral Discrimination of Chiral Macrocyclic Paramagnetic Metal Complexes by NMR Techniques≠

Silvio Aime, Mauro Botta, Simonetta Geninatti Crich, Enzo Terreno, Pier Lucio Anelli, Fulvio Uggeri

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 127 KB

english, 1999

28

Contrast Agents for Magnetic Resonance Imaging: A Novel Route to Enhanced Relaxivities Based on the Interaction of a GdIII Chelate with Poly-β-cyclodextrins

Silvio Aime, Mauro Botta, Luca Frullano, Simonetta G. Crich, Giovanni B. Giovenzana, Roberto Pagliarin, Giovanni Palmisano, Massimo Sisti

Journal:

Chemistry - A European Journal

Year:

1999

Language:

english

File:

PDF, 162 KB

english, 1999

29

A p(O2)-Responsive MRI Contrast Agent Based on the Redox Switch of Manganese(II / III) – Porphyrin Complexes

Silvio Aime, Mauro Botta, Eliana Gianolio, Enzo Terreno

Journal:

Angewandte Chemie International Edition

Year:

2000

Language:

english

File:

PDF, 110 KB

english, 2000

30

A Calix[4]arene GdIII Complex Endowed with High Stability, Relaxivity, and Binding Affinity to Serum Albumin

Silvio Aime, Alessandro Barge, Mauro Botta, Alessandro Casnati, Marco Fragai, Claudio Luchinat, Rocco Ungaro

Journal:

Angewandte Chemie

Year:

2001

Language:

english

File:

PDF, 107 KB

english, 2001

31

Compartmentalization of a Gadolinium Complex in the Apoferritin Cavity: A Route To Obtain High Relaxivity Contrast Agents for Magnetic Resonance Imaging

Silvio Aime, Luca Frullano, Simonetta Geninatti Crich

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

32

Novel pH-Reporter MRI Contrast Agents

Silvio Aime, Daniela Delli Castelli, Enzo Terreno

Journal:

Angewandte Chemie

Year:

2002

Language:

english

File:

PDF, 69 KB

english, 2002

33

Non-covalent Conjugates between Cationic Polyamino Acids and GdIII Chelates: A Route for Seeking Accumulation of MRI-Contrast Agents at Tumor Targeting Sites

Silvio Aime, Mauro Botta, Elena Garino, Simonetta Geninatti Crich, Giovanni Giovenzana, Roberto Pagliarin, Giovanni Palmisano, Massimo Sisti

Journal:

Chemistry - A European Journal

Year:

2000

Language:

english

File:

PDF, 245 KB

english, 2000

34

{DOTA-bis(amide)}lanthanide Complexes: NMR Evidence for Differences in Water-Molecule Exchange Rates for Coordination Isomers

Shanrong Zhang, Zoltan Kovacs, Shawn Burgess, Silvio Aime, Enzo Terreno, A. Dean Sherry

Journal:

Chemistry - A European Journal

Year:

2001

Language:

english

File:

PDF, 246 KB

english, 2001

35

High-Relaxivity Contrast Agents for Magnetic Resonance Imaging Based on Multisite Interactions between a β-Cyclodextrin Oligomer and Suitably Functionalized GdIII Chelates

Silvio Aime, Mauro Botta, Franco Fedeli, Eliana Gianolio, Enzo Terreno, Pierlucio Anelli

Journal:

Chemistry - A European Journal

Year:

2001

Language:

english

File:

PDF, 446 KB

english, 2001

36

Molecular Dynamics Simulation of [Gd(egta)(H2O)]− in Aqueous Solution: Internal Motions of the Poly(amino carboxylate) and Water Ligands, and Rotational Correlation Times

Fabrice Yerly, Kenneth I. Hardcastle, Lothar Helm, Silvio Aime, Mauro Botta, André E. Merbach

Journal:

Chemistry - A European Journal

Year:

2002

Language:

english

File:

PDF, 366 KB

english, 2002

37

Cover Picture

Fabrice Yerly, Kenneth I. Hardcastle, Lothar Helm, Silvio Aime, Mauro Botta, André E. Merbach

Journal:

Chemistry - A European Journal

Year:

2002

Language:

english

File:

PDF, 47 KB

english, 2002

38

Heterodinuclear LnNa Complexes with an Asymmetric Macrocyclic Compartmental Schiff Base

Mauro Botta, Umberto Casellato, Cristina Scalco, Sergio Tamburini, Patrizia Tomasin, Pietro A. Vigato, Silvio Aime, Alessandro Barge

Journal:

Chemistry - A European Journal

Year:

2002

Language:

english

File:

PDF, 211 KB

english, 2002

39

A Calix[4]arene GdIII Complex Endowed with High Stability, Relaxivity, and Binding Affinity to Serum Albumin

Silvio Aime, Alessandro Barge, Mauro Botta, Alessandro Casnati, Marco Fragai, Claudio Luchinat, Rocco Ungaro

Journal:

Angewandte Chemie International Edition

Year:

2001

Language:

english

File:

PDF, 83 KB

english, 2001

40

Compartmentalization of a Gadolinium Complex in the Apoferritin Cavity: A Route To Obtain High Relaxivity Contrast Agents for Magnetic Resonance Imaging

Silvio Aime, Luca Frullano, Simonetta Geninatti Crich

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 97 KB

english, 2002

41

Novel pH-Reporter MRI Contrast Agents

Silvio Aime, Daniela Delli Castelli, Enzo Terreno

Journal:

Angewandte Chemie International Edition

Year:

2002

Language:

english

File:

PDF, 69 KB

english, 2002

42

Isolation and 13C-NMR characterization of an insoluble proteinaceous fraction from substantia nigra of patients with parkinson's disease

Silvio Aime, Bruno Bergamasco, Mariano Casu, Giuseppe Digilio, Mauro Fasano, Sabrina Giraudo, Leonardo Lopiano

Journal:

Movement Disorders

Year:

2000

Language:

english

File:

PDF, 58 KB

english, 2000

43

Supramolecular Adducts between Poly-L-arginine and [TmIIIdotp]: A Route to Sensitivity-Enhanced Magnetic Resonance Imaging–Chemical Exchange Saturation Transfer Agents

Silvio Aime, Daniela Delli Castelli, Enzo Terreno

Journal:

Angewandte Chemie

Year:

2003

Language:

english

File:

PDF, 93 KB

english, 2003

44

Tunable Imaging of Cells Labeled with MRI-PARACEST Agents

Silvio Aime, Carla Carrera, Daniela Delli Castelli, Simonetta Geninatti Crich, Enzo Terreno

Journal:

Angewandte Chemie

Year:

2005

Language:

english

File:

PDF, 152 KB

english, 2005

45

Highly Sensitive MRI Chemical Exchange Saturation Transfer Agents Using Liposomes

Silvio Aime, Daniela Delli Castelli, Enzo Terreno

Journal:

Angewandte Chemie

Year:

2005

Language:

english

File:

PDF, 107 KB

english, 2005

46

From Spherical to Osmotically Shrunken Paramagnetic Liposomes: An Improved Generation of LIPOCEST MRI Agents with Highly Shifted Water Protons

Enzo Terreno, Claudia Cabella, Carla Carrera, Daniela Delli Castelli, Roberta Mazzon, Simona Rollet, Joseph Stancanello, Massimo Visigalli, Silvio Aime

Journal:

Angewandte Chemie

Year:

2007

Language:

english

File:

PDF, 96 KB

english, 2007

47

Reduction/Dissolution of a β-MnOOH Nanophase in the Ferritin Cavity To Yield a Highly Sensitive, Biologically Compatible Magnetic Resonance Imaging Agent

Ferenc Krisztián Kálmán, Simonetta Geninatti-Crich, Silvio Aime

Journal:

Angewandte Chemie

Year:

2010

Language:

english

File:

PDF, 453 KB

english, 2010

48

YbIII-HPDO3A: A Dual pH- and Temperature-Responsive CEST Agent

Dr. Daniela Delli Castelli, Prof. Enzo Terreno, Prof. Silvio Aime

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 386 KB

english, 2011

49

Use of Labile Precursors for the Generation of Hyperpolarized Molecules from Hydrogenation with Parahydrogen and Aqueous-Phase Extraction

Dr. Francesca Reineri, Dr. Alessandra Viale, Dr. Silvano Ellena, Dr. Tommaso Boi, Dr. Valeria Daniele, Prof. Roberto Gobetto, Prof. Silvio Aime

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 298 KB

english, 2011

50

Supramolecular Adducts between Poly-L-arginine and [TmIIIdotp]: A Route to Sensitivity-Enhanced Magnetic Resonance Imaging–Chemical Exchange Saturation Transfer Agents

Silvio Aime, Daniela Delli Castelli, Enzo Terreno

Journal:

Angewandte Chemie International Edition

Year:

2003

Language:

english

File:

PDF, 93 KB

english, 2003